A PyTorch Basecaller for Oxford Nanopore Reads
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Updated
Feb 20, 2026 - Python
A PyTorch Basecaller for Oxford Nanopore Reads
Megalodon is a research command line tool to extract high accuracy modified base and sequence variant calls from raw nanopore reads by anchoring the information rich basecalling neural network output to a reference genome/transriptome.
Methylation/modified base calling separated from basecalling.
Research release basecalling models and configurations
Basecalling configuration prediction from FASTQ files
modPhred is a pipeline for detection of DNA/RNA modifications from raw ONT data
Nanopore direct RNA basecaller
snakemake workflow for basecalling and demultiplexing of ONT sequencing data
[NeurIPS 2024] A Multi-task Benchmark Dataset for Nanopore Sequencing.
A self-supervised foundation model for raw nanopore signals.
A Snakemake workflow for basecalling and demultiplexing of Oxford Nanopore data using Dorado.
Quickstart to Bioinformatics & Biomedical AI.
Cost-effective and scalable Oxford Nanopore Technologies (ONT) basecalling on AWS using Dorado, Nextflow, and AWS Batch with horizontal GPU scaling
Novel basecaller, jointly processing raw and event data from ONT nanopore, basec on encoder-decoder + attention architecture
Benchmarking several NVIDIA GPUs with dorado
nanoRMS2 is a pipeline for detection of DNA/RNA modifications from raw ONT data
Nextflow pipeline to process ONT adaptive sampling runs (basecalling, mapping, statistics)
GPU 碱基识别 SDK → 昇腾 Ascend 910B 迁移与基线工程文档(脱敏公开版)
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